Effect Of Training On PPARGC1A And FNDC5 Gene Expression In Thoroughbred Horses: PGC-1? and irisin, encoded by PPARGC1A and FNDC5 genes, play key roles in mediating the beneficial effects of exercise. This study investigated the responses of PPARGC1A and FNDC5 to training and found a significant increase in gene expression, independent of myostatin genotype.
McGivney B, Herdan C, Gough K, Katz L, Hill EW. Equine Veterinary Journal Supplement. 2014 Jun;(46):35.
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